General Information

Activities

Welcome to the Second Edition of the Virtual World Conference on Luteinizing Hormone in ART: A New Galaxy is Born! This new virtual meeting has the objective of exploring luteinizing activity during folliculogenesis and beyond. The unique virtual format adopted this year is an exciting journey that will take you to new dimensions in ART. The journey starts with a pre-event survey that queries current knowledge. These will be supplemented with additional surveys in real-time during online presentations and post-lecture surveys to gauge the learning experience.

This year’s virtual meeting started on 7 September 2020 and ended on 31 December 2020, and featured 12 video lectures released throughout the meeting period. In addition, an additional 12 Meet the Expert sessions were streamed live once a week, which provided the opportunity for questions and answers. The Call for Abstracts started on 19 September with the deadline for submission on 24 October. Two winning abstracts were chosen, and the winning abstracts were presented online during the closing ceremony on 14 November. By completing all three surveys, participants received a diploma signed by all Chairs. An application has been submitted to EACCME for the 6 live Meet the Expert events. Those submitting an abstract received one year of free registration to the Poseidon website www.groupposeidon.com

However, the virtual meeting doesn’t stop there. A library was freely available for all participants with a collection of articles related to the program. During the meeting, participants could visit the chat room to discuss interesting topics and debate with colleagues, just like at any meeting.

It is hoped that you found this rich online learning experience to be of benefit in ongoing education on the fascinating role of luteinizing hormone in ART.

Overview

The role of luteinizing hormone (LH) during folliculogenesis has intrigued the scientific and medical community for at least three decades. There is now an emerging galaxy of research that is exploring this enigmatic subject.

The availability of recombinant drugs is offering, for the first time, the opportunity to examine the role of follicle stimulating hormone and LH separately. An emerging topic during last year’s conference was the role of LH supplementation in improving outcomes in a subgroup of low prognosis patients selected according to the POSEIDON classification.

During this online journey, the management of these low prognosis patients’ was discussed in detail. Notably, we moved beyond controlled ovarian stimulation to further investigate the involvement of LH in personalizing the luteal phase and in male infertility. In addition, the extra-gonadal effects of LH, including potential immunomodulation at the endometrium, is part of the agenda.
Following the precedent set at last year’s conference, considerable time was devoted to basic science, alongside such controversial issues as progesterone rise and pharmacogenomics. This year we had attracted prominent scientists from the worlds of endocrinology, andrology, immunology, and embryology to take part in our engaging exploration of the LH galaxy.

Learning Objectives

The online journey left with the ability of users;

  • Understand the importance of luteinizing activity during folliculogenesis and beyond.
  • Understand the dynamics of hypothalamic-pituitary axis in the pathogenesis of hypo- and normo-gonadotropic amenorrhea.
  • Comprehend the concept of relative gonadotropin deficiency.
  • Discuss and debate the management of low prognosis patients.
  • Comprehend the clinical utility of the POSEIDON classification for the management of low prognosis women.
  • Discover the clinical relevance of LH supplementation in ART.
  • Appreciate the clinical relevance and pathogenesis of the progesterone rise during COS.
  • Analyse the relevance of LH during the luteal phase and Introduce the concept of individualized luteal phase support.
  • Explore the potential of LH in male infertility.

Target Audience

This programme was designed for clinicians and biologists working in assisted reproductive medicine, who wanted to acquire up-to date information to improve their current practice.

Chairs

Carlo Alviggi
Federico II University
Naples, Italy

Sandro C. Esteves
Androfert – Andrology and Human Reproduction Clinic
Campinas, Brazil

Robert Fischer
Fertility Centre Hamburg
Hamburg, Germany

Peter Humaidan
Fertility Clinic, Skive Regional Hospital
Faculty of Health, Aarhus University
Aarhus, Denmark

Accreditation

An application has been submitted to EACCME for the accreditation of the 6 live Meet the Expert events.

Language

The official language of this virtual conference is English.

CME Provider

Med.E.A – Medical Education Academy
Chloe Xilinas: Programme and Relations Manager in Medical Education
chloe.xilinas@medea.academy
www.medea.academy

Faculty

alviggi

Carlo Alviggi

Naples, Italy

esteves-small

Sandro C. Esteves

Campinas, Brazil

fisher-small

Robert Fischer

Hamburg, Germany

hugues

Jean-Noël Hugues

Paris, France

humaidan-small

Peter Humaidan

Aarhus University

Lehert

Philippe Lehert

Louvain, Belgium

Makrigiannakis

Antonis Makrigiannakis

Heraklion, Greece

fenning

Nick Raine-Fenning

Nottingham, UK

santi

Daniele Santi

Modena, Italy

Sirard

Marc-André Sirard

Québec, Canada

Sunkara-small

Sesh K. Sunkara

London, UK

ubaldi-small

Filippo M. Ubaldi

Rome, Italy

Agenda

Scientific programme

Session I– Moving away from earth: lessons from gonadotropins system

L1 Gonadotropins during ovarian cycles: the galaxy we know
Marc-André Sirard, Canada
L2 Hypothalamic amenorrhea and PCOS: two sides of the moon
Antonis Makrigiannakis, Greece

L3 The role of LH in male infertility: an altered connection between space and earth
Sandro Esteves
L4 Isoforms and polymorphisms of gonadotropins and their receptors in human reproduction: a partial eclipse
Daniele Santi, Italy

Session II – Flying through the stars: how to maximize success in controlled ovarian stimulation

L5 The periodic comet of POR: the novel POSEIDON classification
Sandro C. Esteves, Brazil
L6 Orbiting around clinical practice: management of the four POSEIDON groups
Carlo Alviggi, Italy

L7 Progesterone rise: the black hole of controlled ovarian stimulation
Jean-Noël Hugues, France
L8 Ongoing pregnancy rate as a valid endpoint: mapping a new star system
Sesh Sunkara, UK

Session III – A new universe to explore: medical trends in ART

L9 Antral follicle count: an “objective” dimension?
Nick Raine-Fenning, UK
L10 Follicular waves during the natural cycle: use of Duo-Stim in POSEIDON groups
Filippo M. Ubaldi, Italy

L11 Ovulation triggering: the big bang of an adequate luteal phase
Peter Humaidan, Denmark       
L12 Landing in Real World “Data”
Philippe Lehert, Belgium

Funding

Med.E.A Srl educational programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products.

These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of Med.E.A. Srl. This educational activity is supported by an independent grant from the Healthcare business of Merck KGaA, Darmstadt, Germany.

Video Lectures

Meet The Expert

Sirard

Marc-André Sirard

Québec, Canada

Makrigiannakis

Antonis Makrigiannakis

Heraklion, Greece

esteves-small

Sandro C. Esteves

Campinas, Brazil

santi

Daniele Santi

Modena, Italy

fenning

Nick Raine-Fenning

Nottingham, UK

ubaldi-small

Filippo M. Ubaldi

Rome, Italy

humaidan-small

Peter Humaidan

Aarhus University

Lehert

Philippe Lehert

Louvain, Belgium